Nandrolone Phenylpropionate(Durabolin) Raws Powder CAS：62-90-8

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Nandrolone Phenylpropionate (NPP), commonly known as "Durabolin", is a synthetic anabolic steroid with the chemical name **19-nortestosterone phenylpropionate**. It is one of the earliest developed short-acting nandrolone drugs. Compared with its more well-known long-acting version **Nandrolone Decanoate (Deca-Durabolin)**, NPP has a shorter ester chain, so it takes effect faster but has a shorter duration of action.

The following is a detailed introduction to NPP:

### **Physical and chemical properties**

1. **Chemical structure**:

- Chemical name: **(17β)-3-Oxoestr-4-en-17-yl 3-phenylpropionate**

- Molecular formula: C27H34O3

- Molecular weight: 406.56 g/mol

- CAS number: 62-90-8

2. **Physical properties**:

- Appearance: White or nearly white crystalline powder.

- Solubility: Soluble in lipids, but insoluble in water.

- Melting point: 93-99°C.

3. **Drug type**:

- Anabolic steroid with low androgenicity and high anabolic activity.

### **Pharmacological action**

1. **Main action**:

- Enhances protein synthesis and nitrogen retention, which helps muscle repair and growth.

- Stimulates erythropoiesis, increases red blood cell count, and enhances endurance.

- Increases bone density and strengthens bones.

- Reduces collagen degradation and promotes joint and ligament repair.

2. **Difference from Nandrolone Decanoate**:

- NPP has a shorter ester and takes effect quickly after injection, but requires more frequent dosing.

- Compared with Decanoate esters, NPP has a lower water retention effect, so it is more suitable for users who pursue "clean" muscle gain.

### **Dosage and Usage**

1. **Common Dosage**:

- **Therapeutic Use** (e.g. Osteoporosis or Anemia): The usual dose is 50-100 mg/week, divided into two injections.

- **Bodybuilding and Sports Use**:

- Beginners: 100-200 mg/week (two injections).

- Intermediate Users: 300-400 mg/week (two to three injections).

- Advanced Users: 400-600 mg/week.

2. **Usage Cycle**:

- NPP is usually used in shorter cycles (6-8 weeks) and is more suitable for rapid muscle gain or fat loss due to its rapid onset of action.

- It is also often used in combination with other drugs (such as testosterone esters, Winstrol or Trenbolone) to achieve synergistic effects.

3. **Usage**:

- NPP is usually used in the form of intramuscular injections, most commonly in the thigh or buttocks muscles.

- Each injection dose should be controlled at around 100 mg to reduce discomfort at the injection site.

### **Half-life and pharmacokinetics**

1. **Half-life**:

- The half-life of NPP is **3-4 days**.

- Its short-acting nature means that it needs to be injected every 2-3 days to maintain a stable blood concentration.

2. **Onset of action**:

- It starts to take effect about 24 hours after injection and takes about 48 hours to reach peak concentration.

3. **Detection time**:

- The metabolites of NPP can be detected in the body for a long time, generally **12-18 months**, so there is a risk of being detected when used in sports competitions.

### **Cycling plan**

#### Example 1: Muscle-building cycle (8 weeks)

- **Weeks 1-8**:

- NPP: 300-400 mg/week (injected twice).

- Testosterone Propionate: 200-300 mg/week.

- **Ancillary medications**:

- Aromatase Inhibitors (such as Arimidex) to prevent estrogen-related side effects.

#### Example 2: Fat-cutting cycle (6 weeks)

- **Weeks 1-6**:

- NPP: 200-300 mg/week.

- Winstrol: 50 mg/day (oral or injection).

- Testosterone support (such as Test Propionate): 150-200 mg/week.

### **Side effects and risks**

1. **Common side effects**:

- **Estrogenic effects**: such as water retention, male breast development (Gynecomastia). Anti-estrogen drugs (such as Aromatase Inhibitors) should be used.

- **Androgenic effects**: Hair loss, acne (less common due to its low androgenic activity).

- **Sexual function suppression**: Long-term use may suppress endogenous testosterone production.

- **Dyslipidemia**: Reduces HDL ("good" cholesterol) levels and increases cardiovascular risk.

2. **Specific risks**:

- Hepatotoxicity: Injectable drugs generally have little effect on the liver.

- Hypertension: Due to water retention and increased red blood cell production, it may cause high blood pressure.

- Joint pain relief: Although it has the effect of lubricating joints, symptoms may worsen after stopping use.

### **Applicable groups and contraindications**

1. **Applicable groups**:

- Patients diagnosed by a doctor who need to enhance physical fitness and promote muscle repair.

- High-level athletes and bodybuilding enthusiasts (pay attention to potential competitive doping issues).

2. **Contraindications**:

- Pregnant or lactating women.

- Men at risk of prostate cancer or breast cancer.

- Patients with cardiovascular disease and hypertension.

### **Summary**

Nandrolone Phenylpropionate is an effective short-acting anabolic steroid with low androgenicity and high protein synthesis capacity. It is widely used for muscle growth, sports recovery and the treatment of bone-related diseases. However, its use requires strict control of dosage and cycle, and combined with auxiliary drugs to reduce side effects. In addition, since it is banned in competitive sports, it is necessary to fully understand the relevant rules and risks before use.

Nandrolone Phenylpropionate (Durabolin) is a synthetic anabolic steroid that is often used to treat diseases or as a muscle-building and recovery tool for athletes and bodybuilders. The following is a detailed introduction to its applicable population, working principle, and usage and dosage:

### **Applicable population**

1. **Medical use**:

- **Osteoporosis patients**: Helps increase bone density and reduce the risk of fractures.

- **Anemia patients**: Improve hemoglobin levels by stimulating red blood cell production.

- **Chronic wasting disease patients**: Such as HIV/AIDS-related weight loss or cancer patients, used to enhance muscle mass and physical strength.

2. **Athletes and bodybuilders**:

- Athletes who pursue muscle growth, strength improvement, and athletic performance.

- Bodybuilders who need to quickly recover from training fatigue.

- Professional athletes who want to improve muscle mass but avoid residual detection of long-acting steroids (such as Nandrolone Decanoate).

### **How ​​it works**

The main mechanisms of action of Nandrolone Phenylpropionate include:

1. **Promote protein synthesis**:

- Increase muscle mass and strength by improving nitrogen balance in muscle cells and stimulating muscle synthesis.

2. **Enhance erythropoiesis**:

- Promote the release of erythropoietin (EPO), increase the number of red blood cells in the blood, and improve endurance and oxygen delivery capacity.

3. **Improve collagen synthesis**:

- Promote the repair and strength of joints and ligaments, and reduce the risk of sports injuries.

4. **Reduce muscle breakdown**:

- Inhibit the effects of catabolic hormones (such as cortisol), which helps protect muscles.

5. **Fast metabolism**:

- Compared with Decanoate, the Phenylpropionate version has a shorter duration of action (1-3 days), so it takes effect quickly and metabolizes quickly, which is more suitable for users who need short-term effects or avoid drug testing.

### **Usage and Dosage**

#### **1. Medical Use**:

- **Dosage**: Usually 50-100 mg per week.

- **Cycle**: Depending on the condition, it can be used for a long or short period of time, and requires doctor's guidance.

#### **2. Sports and Bodybuilding Use**:

- **Dosage**:

- Beginners: 100-200 mg per week.

- Intermediate users: 200-400 mg per week.

- Advanced users: 400-600 mg per week (high doses should pay attention to side effects).

- **Cycle**: Usually 6-8 weeks is a cycle.

- **Injection frequency**: Due to the short half-life (2-4 days), inject once every 2-3 days to maintain a stable blood drug concentration.

#### **Precautions**:

- **Combined with other drugs**: Often used in combination with testosterone drugs to maintain normal hormone levels in the body.

- **Auxiliary drugs**: Anti-estrogen drugs (such as Clomid or Nolvadex) and HCG are required during and after the cycle (PCT) to prevent endocrine disorders.

- **Injection site**: It is recommended to rotate the injection site (such as buttocks or thighs) to avoid local tissue inflammation or nodules.

### **Side effects and risks**

1. **Male-specific side effects**:

- Testosterone suppression: Reduced natural testosterone levels in the body may lead to sexual dysfunction.

- Estrogen-related: such as edema, breast development (male breast hyperplasia).

2. **Female-specific side effects**:

- Acne, increased body hair, and deepening of the voice are manifestations of androgenization.

3. **Other risks**:

- Cardiovascular problems: Dyslipidemia may increase the risk of cardiovascular disease.

- Liver stress: Although the toxicity is low, long-term use may increase the burden on the liver.

- Drug dependence: Abuse may lead to psychological dependence or drug detection problems.

### **Summary recommendations**

- **Medical users** should strictly follow the doctor's instructions and avoid adjusting the dosage on their own.

- **Athletes and bodybuilders** should fully understand its legal status (controlled substance in most countries) and potential side effects before use, and ensure that it cooperates with post-cycle treatment (PCT).

- **Health check**: Regularly monitor liver function, blood lipid levels and hormone levels to ensure physical condition.

Nandrolone Phenylpropionate (NPP), also known as Durabolin, is a synthetic anabolic steroid that is usually sold in the form of raw powder for preparation into injections or other dosage forms. NPP is popular in bodybuilding, athletic performance enhancement, and certain medical treatments for its relatively fast duration of action, good tolerability, and versatility. Here are the detailed benefits of NPP:

### **1. Enhances Muscle Growth and Strength**

- **Promotes Protein Synthesis**: NPP supports the growth and repair of muscle tissue by enhancing the production of protein within muscle cells.

- **Nitrogen Balance Effect**: NPP helps increase nitrogen levels in muscles, maintaining the body in an anabolic state that is beneficial for muscle growth.

- **Accelerated Recovery**: NPP can reduce muscle soreness and fatigue after training, helping athletes recover quickly to cope with high-intensity training.

### **2. Improves Bone Density**

- **Promotes Bone Mineral Deposition**: NPP has a positive effect on bone tissue, which can increase bone density and thus prevent osteoporosis.

- **Activate bone marrow hematopoiesis**: In some medical applications, NPP can improve the hematopoiesis of the bone marrow and is used to treat certain anemias.

### **3. Improve joint health**

- **Relieve joint pain**: NPP helps lubricate joints and relieve discomfort caused by training or arthritis by stimulating the secretion of synovial fluid.

- **Anti-inflammatory properties**: NPP has a certain effect on relieving joint inflammation and is suitable for people who need to engage in high-intensity exercise frequently.

### **4. Improve red blood cell production**

- **Promote red blood cell production**: NPP stimulates the secretion of erythropoietin, thereby increasing the number of red blood cells and the oxygen-carrying capacity of the blood. This is very beneficial for improving exercise endurance and physical performance.

- **Improve anemia symptoms**: NPP is often used to treat certain anemia diseases and improves the patient's health by increasing the number of red blood cells.

### **5. Improve fat metabolism**

- **Enhance fat burning**: NPP helps reduce body fat and improve body shape by increasing the metabolic rate.

- **Maintain muscle while reducing fat**: In the case of reduced calorie intake, NPP helps maintain muscle mass and reduce muscle loss from fat loss.

### **6. Potential medical benefits for female patients**

- **Treat breast cancer**: In some cases, NPP is used as an adjuvant therapy for breast cancer patients to inhibit cancer cell growth.

- **Regulate hormone imbalance**: It can be used to treat hormone-related problems such as osteoporosis or hormone deficiency in postmenopausal women.

### **7. Potential benefits for cardiovascular health**

- **Increase HDL cholesterol (good cholesterol)**: Compared with other anabolic steroids, NPP has less negative effects on blood lipids and may even improve HDL levels.

- **Improve vascular elasticity**: By reducing inflammation and promoting tissue repair, NPP may have a positive effect on vascular health.

### **8. Fast onset of action, short half-life**

- **Fast onset of action**: Due to its phenol propionate structure, NPP has a faster onset of action than Nandrolone Decanoate (Deca-Durabolin), making it suitable for users who need quick results.

- **Easier to adjust dosage**: NPP's short half-life allows users to adjust dosage more quickly or stop taking the drug if necessary, reducing the risk of potential side effects.

### **9. Relatively mild side effects**

- **Low androgenicity**: NPP has low androgenic activity, so it may reduce the occurrence of side effects such as hair loss and acne compared to other steroids.

- **Low hepatotoxicity**: NPP injection form is less toxic to the liver and is suitable for patients or athletes who need long-term treatment.

### **10. Medical application areas**

- **Treating tissue wasting after trauma or surgery**: NPP can be used to help restore the body's lost weight and muscle after surgery or serious illness.

- **Improving malnutrition caused by chronic diseases**: In some cases, NPP is used to enhance nutrient absorption and improve body function.

### **Precautions**

Despite the significant benefits of NPP, abuse or long-term use may lead to side effects such as endocrine disruption (testosterone suppression), water and sodium retention, dyslipidemia, etc. Appropriate dosage and cycle management are essential and are recommended for use under the supervision of a professional physician or qualified medical personnel.

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