Oxymetholone (Anadrol) Raws Powder CAS：434-07-1

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Oxymetholone, trade name *Anadrol*, is a synthetic androgenic and anabolic steroid (AAS). It was first developed in the 1960s to treat anemia, bone marrow failure, and in some cases severe weight loss. It was later widely used by bodybuilders and fitness enthusiasts due to its significant muscle-building and performance-enhancing effects, but it also came with a higher risk of side effects.

### **Physical and Chemical Properties**

- **Molecular formula**: C21H32O3

- **Molecular Weight**: 332.48 g/mol

- **Appearance**: Usually white or nearly white crystalline powder.

- **Solubility**:

- Hardly soluble in water.

- Soluble in organic solvents such as chloroform, ethanol and dimethyl sulfoxide (DMSO).

- **Melting point**: 172–180°C.

As a 17α-alkylated steroid, Oxymetholone's chemical structure has been modified to persist longer in the liver, thereby improving oral bioavailability.

### **Mechanism of action**

Oxymetholone works by enhancing anabolic effects, including:

1. **Increase red blood cell production**: Stimulate the bone marrow to produce more red blood cells, thereby improving blood oxygen transport capacity.

2. **Promote protein synthesis**: Accelerate protein synthesis in muscle tissue and significantly increase muscle volume.

3. **Inhibit protein decomposition**: Reduce the decomposition rate of protein in muscle tissue.

4. **Improved Nitrogen Balance**: Supports muscle growth by reducing nitrogen loss and improving nitrogen retention.

### **DOSAGE**

1. **Medical Use** (Treatment of anemia, etc.): The recommended dose is 50 mg daily, and the dose can be adjusted according to the patient's response.

2. **Non-Medical Use** (Bodybuilding/Performance Enhancement):

- **Common dosage**: 25-100 mg/day.

- **HIGH DOSES**: Some extreme users may reach 150 mg/day, but the risk is significantly increased.

- **Note**: Using too high a dose will not significantly increase the effect, but may significantly increase the risk of side effects.

### **Half-life and Pharmacokinetics**

- **Half-life**: Approximately 9 hours.

- **Detection Time**: May be detected in the body for up to 8 weeks.

- **Metabolism**: Mainly metabolized in the liver, and metabolites are excreted in the urine.

Due to its short half-life, Oxymetholone usually requires multiple daily doses to maintain stable blood levels.

### **Cycle Suggestions**

Oxymetholone is typically used for rapid weight and strength gains in short cycles. Typical cycles are as follows:

1. **Cycle length**: 4-6 weeks (no more than 6 weeks is recommended to reduce liver toxicity).

2. **Superimposed with other drugs**:

- **Muscle Building Cycle**: Often used in combination with other steroids such as Testosterone and Deca-Durabolin.

- **Shorter Fat Phase**: Not usually used during fat loss phases due to its significant water retention effect.

3. **Dose Gradation**: Some users choose to gradually increase the dose to assess body response and reduce side effects.

### **Effect**

- **advantage**:

- Rapid weight gain (possible weight gain of 10-15 kg in 4-5 weeks, mainly muscle and water).

- Dramatically improves strength and athletic performance.

- Achieve explosive muscle growth in a short period of time.

- **shortcoming**:

- A large part of the weight gain is water, which may be lost quickly after stopping the drug.

- Highly hepatotoxic.

### **side effect**

Because of its potency and chemical modifications, Oxymetholone has a higher risk of side effects, including:

#### **1. Hepatotoxicity**

- As a 17α-alkylated steroid, there is significant stress on the liver and may lead to:

- Abnormal liver function.

- Cholestatic jaundice.

- Long-term use at high doses may cause severe liver damage or liver cancer.

#### **2. Hormone related issues**

- **Estrogen Related Side Effects**:

- Although Oxymetholone itself is not converted to estrogen, it can indirectly increase estrogen-like effects (eg, water retention, breast hyperplasia).

- **Androgen Related Side Effects**:

- Acne, thinning hair (androgenic alopecia).

- Increased risk of prostate enlargement.

#### **3. Cardiovascular health**

- Increases low-density lipoprotein (LDL) and decreases high-density lipoprotein (HDL) levels.

- Long-term use may increase the risk of hypertension and atherosclerosis.

#### **4. Mental and emotional changes**

- Some users report increased anxiety, irritability, and aggression.

#### **5. Inhibit endogenous testosterone**

- Prolonged use will significantly suppress your own testosterone production, and post-cycle therapy* (PCT) may be required to restore endogenous hormone levels after discontinuation.

### **Summarize**

Oxymetholone is a very potent anabolic steroid that significantly promotes weight and strength gains in the short term, but comes with high hepatotoxicity and a host of potential risks. It is recommended to fully weigh the pros and cons before use and always follow the following principles:

- **Short Cycle**: No more than 6 weeks.

- **Appropriate dose**: Control at 50-100 mg daily.

- **Post Cycle Recovery**: Restoration of endogenous hormones using PCT.

- **Monitor Health**: Regularly monitor liver function, blood lipids and other related health indicators.

Oxymetholone (Anadrol) is an anabolic steroid (AAS) widely used in medicine and fitness. The following is a detailed introduction to its applicable population, working principle, and usage and dosage:

### **1. Applicable population**

#### **Medical use**:

1. **Anemia patients**: Oxymetholone was originally used to treat anemia caused by insufficient red blood cell production (such as aplastic anemia).

2. **Cachexia patients**: Help maintain weight and increase muscle mass, especially weight loss caused by diseases (such as AIDS, cancer).

#### **Fitness use**:

1. **Muscle gain needs**: Suitable for bodybuilders or power athletes who want to quickly increase muscle size and strength.

2. **Strength breakthrough period**: Used to help athletes achieve breakthroughs in the strength growth plateau period.

3. **Pre-season muscle gain cycle**: Short-term use to quickly increase weight and muscle mass, usually used as an "opening steroid"

#### **Not suitable for**:

- Pregnant or lactating women.

- People who are allergic to anabolic steroids.

- Patients with a history of severe heart, liver or kidney disease.

- Men with prostate or breast cancer.

### **2. Working principle**

Oxymetholone is a highly effective anabolic steroid with the following mechanism of action:

1. **Enhance protein synthesis**: Stimulates protein synthesis in muscle tissue and promotes muscle growth.

2. **Increases erythropoiesis**: By stimulating the bone marrow, the number of red blood cells is increased, thereby improving blood oxygen transport capacity.

3. **Promote nitrogen retention**: Increases nitrogen retention rate, helping to maintain and increase muscle mass.

4. **Inhibits muscle breakdown**: Reduces the decomposition of cortisol on muscle tissue.

5. **Rapidly increase weight and strength**: Due to the significant increase in water and muscle tissue, weight and strength can be rapidly increased in the initial use.

### **3. Usage and Dosage**

#### **Usage**

- **Oral**: Oxymetholone is usually in the form of tablets and is directly absorbed orally.

- **Dietary Combination**: It is recommended to combine with a high-protein, high-calorie diet to optimize the effect.

- **Cycle Design**: It is usually used in combination with other steroids to reduce the side effects that may be caused by single use.

#### **Dosage**

- **Medical Use**:

- Adults: 50-150mg/day, the specific dosage depends on the patient's condition.

- Adolescents or children: It should be used under the guidance of a professional doctor, and the dosage is relatively low.

- **Fitness Use**:

- Conventional dose: 50-100mg/day.

- High dose (risky): up to 150mg/day, but the side effects may increase significantly.

- Cycle duration: usually 4-6 weeks, not recommended to exceed 6 weeks to avoid liver toxicity.

- Combined use: Oxymetholone is often used in combination with testosterone or other anabolic steroids (such as Nandrolone or Trenbolone) to optimize muscle gain.

### **4. Precautions**

1. **Side effect monitoring**:

- Hepatotoxicity: Oxymetholone puts a lot of pressure on the liver, and it is recommended to check liver function regularly.

- Hormone-related: It may cause edema, hypertension, acne, and gynecomastia (especially at high doses).

- Psychological effects: It may cause mood swings or aggression.

2. **PCT (Post-cycle Recovery)**:

- After use, testosterone recovery therapy (such as HCG, Clomid or Nolvadex) is required to restore natural hormone levels in the body.

3. **Contraindicated combined medications**: Avoid combined use with other hepatotoxic drugs (such as certain antibiotics or analgesics).

4. **Female use**: Due to the possibility of masculinization symptoms (such as deepening of the voice and hair growth), female use should be extremely cautious.

### **Summary**

Oxymetholone is a highly effective but side-effect anabolic steroid suitable for users who want to quickly increase muscle mass and strength in a short period of time. Whether for medical or fitness use, it is necessary to strictly follow the dosage and cycle design and closely monitor the body's response to reduce potential risks.

Oxymetholone, also known as Anadrol, is a powerful anabolic steroid primarily used to promote muscle growth and treat certain medical conditions. Here's a full breakdown of the detailed benefits and potential effects of Oxymetholone:

### **Medical Use Benefits**

1. **Treat anemia**

Oxymetholone was originally developed to treat various types of anemia, particularly aplastic anemia. It improves the blood's oxygen-carrying capacity by stimulating bone marrow to increase red blood cell production and increase hemoglobin levels.

2. **Improve body weight and muscle mass**

Oxymetholone may be used to help patients regain weight and muscle mass in cachexia (significant weight loss and muscle wasting) caused by diseases such as AIDS, cancer, or severe burns.

3. **Promote protein synthesis**

Oxymetholone provides the body with a better environment for muscle repair and recovery by enhancing protein synthesis and nitrogen retention, which is particularly beneficial for post-operative recovery and severe trauma patients.

4. **Alleviate Osteoporosis**

Oxymetholone is used in some cases to relieve symptoms of osteoporosis and reduce the risk of fractures by increasing bone density.

### **Benefits in the field of bodybuilding and sports**

1. **Quickly increase muscle size and strength**

Oxymetholone is one of the most effective steroids for promoting muscle growth. Users are usually able to significantly increase muscle size in a short period of time (such as 4-6 weeks), mainly due to its powerful anabolic effects.

2. **Enhance strength performance**

Anadrol can quickly increase strength, and for strength training athletes or bodybuilders, it can help them press heavier weights more efficiently during training.

3. **Improve training endurance**

Enhanced red blood cell production results in better oxygen delivery, allowing athletes to train longer and with less fatigue.

4. **Significant pumping and muscle congestion**

During use, the vasocongestive effect of the muscles is significantly enhanced, bringing a "pumping" feeling, which is very popular in bodybuilding training.

5. **Improve recovery speed**

Oxymetholone allows athletes to recover faster after training by enhancing protein synthesis and reducing muscle breakdown, thereby shortening rest periods.

### **Unique Advantages**

1. **Beginner Friendly**

Oxymetholone provides significant body changes in the short term, making it attractive to bodybuilders who are new to steroid use, but care must be taken to use it correctly to avoid potential side effects.

2. **Oral form without injection**

Anadrol is an oral steroid, which avoids the cumbersomeness and discomfort of injecting steroids and is convenient and easy to use.

3. **Synergy**

It is often combined with other steroids (such as testosterone or nandrolone) to form a "stack" cycle, further amplifying the effects of muscle growth and strength improvement.

### **Potential Risks and Precautions**

Despite the significant benefits of Oxymetholone, its potential side effects cannot be ignored, including hepatotoxicity, water retention, androgenic alopecia, acne, and possible testosterone suppression. To minimize risk, you should:

- Follow a short cycle (usually no more than 6 weeks).

- Supplement with a liver protectant (such as milk thistle extract or NAC).

- Use as directed by your doctor or under experienced guidance.

- Follow a healthy diet and have regular physical exams to monitor health indicators.

### **Summarize**

Oxymetholone (Anadrol) is a powerful steroid with significant ability to promote muscle growth and improve strength, and provides a medical solution for the treatment of anemia and other health problems. However, correct use and preventing side effects are equally important. For any user, it is critical to understand the mechanisms and potential effects, and dosage and cycles should be carefully controlled to ensure safety and maximum effectiveness.

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