1-4 Butanediol Raws Powder CAS：110-63-4

*1,4-Butanediol (BDO) is an organic compound with the chemical formula \( C_4H_{10}O_2 \). It is a diol with two hydroxyl groups (-OH) in the molecule. The following is detailed information about 1,4-butanediol:

### **Basic Information**

- **Chemical Name**: 1,4-Butanediol (1,4-Butanediol)

- **Molecular Formula**: \( C_4H_{10}O_2 \)

- **Molecular Weight**: 90.12 g/mol

- **Structural Formula**: HO-CH2-CH2-CH2-CH2-OH

- **CAS Number**: 110-63-4

### **Physical Properties**

- **Appearance**: Colorless to light yellow viscous liquid, colorless transparent liquid or powder when the purity is high (may solidify into powder when the ambient temperature is low).

- **Odor**: Slightly sweet.

- **Melting point**: 20-25°C (may be liquid near room temperature)

- **Boiling point**: 230°C

- **Solubility**: Very soluble in water, also soluble in organic solvents such as ethanol and ether.

- **Density**: 1.017 g/cm³ (25°C)

### **Chemical properties**

1,4-Butanediol is a stable compound, but it decomposes at high temperatures or in the presence of catalysts. It is an important raw material for a variety of industrial chemicals and polymers.

- **Reaction properties**:

- It can be dehydrated to tetrahydrofuran (THF) under acid or base catalysis.

- It can be oxidized to succinic acid or γ-butyrolactone under oxidative conditions.

- It can react with acids to form esters.

### **Uses**

1. **Industrial Use**:

- Mainly used as raw materials and intermediates for organic synthesis, such as for the production of tetrahydrofuran (THF), polybutylene terephthalate (PBT), etc.

- Used as a plasticizer or solvent in coatings and adhesives.

2. **Pharmacological Action (Abuse)**:

- After metabolism in the body, it can be converted into γ-hydroxybutyric acid (GHB), which has sedative and anesthetic effects, so it is abused by some people and even called "liquid ecstasy".

### **Pharmacokinetics and Half-Life**

- **Absorption and Metabolism**:

After oral or injection, 1,4-butanediol is quickly absorbed and metabolized into γ-hydroxybutyric acid (GHB) in the body, mainly through the action of alcohol dehydrogenase and aldehyde dehydrogenase in the liver.

- **Half-Life**:

The conversion process to GHB is very fast, and the half-life of its metabolite GHB is usually 30-60 minutes.

- **Excretion**:

Excreted through the kidneys, the metabolites are mainly carbon dioxide and water.

### **Dosage and cycle (abuse)**

**Note**: Any abuse of 1,4-butanediol may lead to serious health risks and legal consequences. The following information is for popular science only and should not be used for actual operations.

- **Dosage**:

Abusers usually take it in liquid form, with a dose range of 1-5 mL, but this depends on personal tolerance. High doses may cause serious adverse reactions.

- **Duration of effect**:

Sedation generally occurs within 30 minutes and lasts for 2-4 hours.

- **Cycle**:

Long-term abuse may lead to dependence, withdrawal symptoms, and damage to the nervous system and liver.

### **Toxicity and safety**

1. **Acute toxicity**:

- High doses may cause loss of consciousness, respiratory depression, and even death.

- Swallowing or accidental ingestion may cause damage to the gastrointestinal tract and nervous system.

2. **Long-term effects**:

- Long-term abuse can lead to physical dependence, liver damage, and nervous system damage.

3. **Legality**:

- In many countries, 1,4-butanediol is listed as a controlled chemical and unauthorized production, possession, or use may be illegal.

### **Precautions**

- Due to the dual use of 1,4-butanediol in industrial and pharmacological fields, abuse of this substance may lead to serious legal problems and health consequences.

- Relevant regulations should be strictly followed and it should only be used for legal industrial production and research purposes.

- If exposed to 1,4-butanediol, please wear appropriate protective equipment, avoid inhalation or swallowing, and dispose of waste properly.

*1,4-Butanediol (BDO) is an organic compound that is widely used in the industrial field and is also used for medical or chemical purposes in some cases. The following is a detailed description of the applicable population, working principle, usage and dosage of 1,4-butanediol raw material powder.

### **Applicable population**

The users of 1,4-butanediol are usually based on its industrial or chemical use, rather than directly applied to ordinary consumers. Specific applicable populations include:

1. **Industrial practitioners**: Chemical companies used to manufacture polymers, plastics, elastomers (such as polyurethane) and solvents.

2. **Scientific researchers**: Experimental researchers engaged in chemical synthesis.

3. **Pharmaceutical industry**: Producers used for drug synthesis under specific conditions.

4. **Legal and compliant manufacturers**: Producers of degradable plastics (such as polybutylene terephthalate, PBAT) or other materials.

Important note: 1,4-butanediol is not suitable for direct use as a food, beverage additive or drug for ordinary consumers.

### **Working Principle**

The role of 1,4-butanediol depends on its specific use:

1. **Chemical raw material**: 1,4-butanediol is an important intermediate that can generate other compounds through chemical reactions, such as:

- Converted into tetrahydrofuran (THF), which is used to make elastic fibers (such as spandex).

- Used in the production of polyurethane and other polymer materials.

2. **Solvent effect**: In some chemical processes, 1,4-butanediol can be used as a solvent, and its good solubility helps to improve production efficiency.

3. **Drug intermediate**: In the pharmaceutical industry, 1,4-butanediol can be used as a precursor for certain drugs (such as sedatives or muscle relaxants).

**Biological metabolism note**: When entering the human body, 1,4-butanediol can be metabolized into pseudo-gamma-aminobutyric acid (GHB), which has a neurosuppressive effect, but may cause serious health risks and should be strictly avoided.

### **Usage and Dosage**

#### 1. **Industrial Use**

- **As a chemical raw material**: Usually added according to process requirements, the specific amount is determined according to the reaction ratio.

- **As a solvent**: The concentration and dosage need to be adjusted according to the solubility requirements.

#### 2. **Scientific Research**

- **Laboratory Dosage**: Strictly calculated according to the experimental design, usually in grams or milliliters, to avoid overdose.

#### 3. **Safety Precautions**

1. For industrial use or professional research purposes only, avoid direct contact with skin, eyes or inhalation of vapor.

2. Store in a sealed container, avoid high temperatures and open flames, and keep ventilated.

3. Wear protective equipment (such as gloves, protective glasses and masks) when using.

**Warning**: 1,4-Butanediol may be abused as an illegal drug, and its direct ingestion can cause serious damage to human health, including but not limited to loss of consciousness, respiratory depression, liver and kidney damage, and even death. When using, you must strictly abide by relevant laws and regulations to ensure legality and compliance.

### Summary

1,4-Butanediol is an important industrial chemical with wide applications in the chemical and pharmaceutical fields. However, its use must be operated by professionals and the dosage must be strictly controlled under the premise of legality and compliance. Non-professionals should avoid contact with or use of such chemicals.

1,4-Butanediol (BDO) is an important organic chemical raw material, which is often transported and stored in powder form. The following is a detailed introduction to the advantages and characteristics of 1,4-butanediol:

### **1. Versatility**

1,4-Butanediol is a widely used chemical intermediate that can be used as a raw material for a variety of industrial and daily products:

- **Polymer manufacturing**: used to produce polymer materials such as polyurethane (PU), polybutylene terephthalate (PBT), and biodegradable plastics (PBAT).

- **Solvent**: In the pharmaceutical, coating, cosmetics and other industries, 1,4-butanediol is an efficient solvent with good solubility.

- **Tetrahydrofuran (THF) synthesis**: Through dehydration reaction, 1,4-butanediol can produce THF, which is a key solvent and intermediate.

### **2. Chemical stability**

1,4-Butanediol powder has the following stability advantages:

- **Easy to store**: BDO in powder form is easy to transport and store, reducing the risk of leakage and volatilization.

- **High purity**: Modern technology allows the purity of 1,4-Butanediol powder to reach more than 99%, ensuring reaction efficiency in downstream applications.

- **Low corrosiveness**: Compared with many chemicals, 1,4-Butanediol has lower corrosiveness and is safer to use.

### **3. Environmental advantages**

1,4-Butanediol and its derivatives are of great significance in the field of green chemical industry:

- **Biodegradable**: Its derivatives such as PBT and PBAT are the main components of degradable plastics and meet environmental protection requirements.

- **Reduced pollution**: Compared with some petrochemical-based materials, the production process of 1,4-Butanediol is developing in a more environmentally friendly direction, such as bio-based BDO technology.

### **4. Wide market demand**

1,4-Butanediol has a huge demand worldwide, and its market share is expanding:

- **Industrial field**: A large amount of BDO and its downstream products are needed in automobile manufacturing, building materials and electronic products.

- **Pharmaceutical field**: As a drug intermediate, 1,4-Butanediol has special application value.

- **Textile industry**: Used to make elastic fibers, polyester and functional fabrics.

### **5. Superior physical properties**

The physical properties of 1,4-Butanediol powder give it unique advantages in many fields:

- **Good hygroscopicity**: Suitable for stability in a humid environment.

- **Easy to mix**: Good compatibility with other substances during chemical reactions and processing.

- **High thermal stability**: Suitable for reactions or processing under high temperature conditions.

### **6. Economical**

The production and use of 1,4-Butanediol powder is economical:

- **High cost performance**: Compared with other solvents or intermediates, BDO has a lower cost.

- **Mature production technology**: There are many efficient production technologies (such as Reppe method and bio-fermentation method) worldwide, and large-scale production reduces unit costs.

- **Reduced waste**: The powder form reduces waste in transportation and use and improves raw material utilization.

### **7. Renewable source**

In recent years, with the growing demand for sustainable development, bio-based 1,4-butanediol has become a research and industrial hotspot:

- **Green synthesis**: Use renewable resources (such as sugars or cellulose) to produce BDO and reduce dependence on petroleum resources.

- **Reduce carbon emissions**: The production process of bio-based BDO can significantly reduce greenhouse gas emissions.

### **Summary**

The advantages of 1,4-butanediol (Raws Powder) are mainly reflected in its versatility, chemical stability, environmental protection characteristics, wide market demand, superior physical properties, economy and renewable sources. As an important chemical raw material, BDO plays an irreplaceable role in industry, medicine, environmental protection and other fields, and its development prospects are very broad.

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